A new paradigm: diagnosis and management of HSCT-associated thrombotic microangiopathy as multi-system endothelial injury

S Jodele, BL Laskin, CE Dandoy, KC Myers, J El-Bietar… - Blood reviews, 2015 - Elsevier
Hematopoietic stem cell transplantation (HSCT)-associated thrombotic microangiopathy (TA-
TMA) is now a well-recognized and potentially severe complication of HSCT that carries a …

New approaches in the diagnosis, pathophysiology, and treatment of pediatric hematopoietic stem cell transplantation-associated thrombotic microangiopathy

S Jodele, CE Dandoy, KC Myers, J El-Bietar… - … and Apheresis Science, 2016 - Elsevier
Hematopoietic stem cell transplantation (HSCT)-associated thrombotic microangiopathy (TA-
TMA) is an understudied complication of HSCT that significantly affects transplant-related …

[HTML][HTML] Pulmonary hypertension after hematopoietic stem cell transplantation

CE Dandoy, R Hirsch, R Chima, SM Davies… - Biology of Blood and …, 2013 - Elsevier
Pulmonary hypertension (PH) is a potentially fatal complication of hematopoietic stem cell
transplantation (HSCT). Given its nonspecific clinical presentation, it is likely that this clinical …

Posttransplant cyclophosphamide is associated with increased cytomegalovirus infection: a CIBMTR analysis

SR Goldsmith, MB Abid, JJ Auletta… - Blood, The Journal …, 2021 - ashpublications.org
Prior studies suggest increased cytomegalovirus (CMV) infection after haploidentical donor
transplantation with posttransplant cyclophosphamide (HaploCy). The role of allograft …

Complement blockade for TA-TMA: lessons learned from a large pediatric cohort treated with eculizumab

S Jodele, CE Dandoy, A Lane… - Blood, The Journal …, 2020 - ashpublications.org
Overactivated complement is a high-risk feature in hematopoietic stem cell transplant
(HSCT) recipients with transplant-associated thrombotic microangiopathy (TA-TMA), and …

The genetic fingerprint of susceptibility for transplant-associated thrombotic microangiopathy

S Jodele, K Zhang, F Zou, B Laskin… - Blood, The Journal …, 2016 - ashpublications.org
Transplant-associated thrombotic microangiopathy (TA-TMA) occurs frequently after
hematopoietic stem cell transplantation (HSCT) and can lead to significant morbidity and …

[HTML][HTML] Variable eculizumab clearance requires pharmacodynamic monitoring to optimize therapy for thrombotic microangiopathy after hematopoietic stem cell …

S Jodele, T Fukuda, K Mizuno, AA Vinks… - Biology of blood and …, 2016 - Elsevier
Thrombotic microangiopathy (TMA) after hematopoietic stem cell transplantation (HSCT)
associated with terminal complement activation, as measured by elevated plasma terminal …

[HTML][HTML] Antibiotic exposure and reduced short chain fatty acid production after hematopoietic stem cell transplant

LE Romick-Rosendale, DB Haslam, A Lane… - Biology of Blood and …, 2018 - Elsevier
Human studies have shown loss of diversity of the gut microbiome following hematopoietic
stem cell transplantation (HSCT) in association with significant gut injury caused by the …

[HTML][HTML] Ruxolitinib as salvage therapy in steroid-refractory acute graft-versus-host disease in pediatric hematopoietic stem cell transplant patients

P Khandelwal, A Teusink-Cross, SM Davies… - Biology of Blood and …, 2017 - Elsevier
We describe our retrospective clinical experience with ruxolitinib for steroid-refractory acute
graft-versus-host disease (GVHD) in pediatric allogeneic hematopoietic stem cell transplant …

EASIX in patients with acute graft-versus-host disease: a retrospective cohort analysis

T Luft, A Benner, S Jodele, CE Dandoy… - The Lancet …, 2017 - thelancet.com
Background Endothelial dysfunction links thrombotic microangiopathy to steroid-refractory
graft-versus-host disease (GVHD) after allogeneic stem-cell transplantation. We aimed to …