Population-based epidemiologic studies have uncovered the high prevalence and wide
severity spectrum of undiagnosed obstructive sleep apnea, and have consistently found that …

Importance Obstructive sleep apnea (OSA) affects 17% of women and 34% of men in the US
and has a similar prevalence in other countries. This review provides an update on the …

Obstructive sleep apnea (OSA) is thought to affect almost 1 billion people worldwide. OSA
has well established cardiovascular and neurocognitive sequelae, although the optimal …

Abstract The Trans-Omics for Precision Medicine (TOPMed) programme seeks to elucidate
the genetic architecture and biology of heart, lung, blood and sleep disorders, with the …

The American Academy of Sleep Medicine (AASM) Sleep Apnea Definitions Task Force
reviewed the current rules for scoring respiratory events in the 2007 AASM Manual for the …

Background Sleep-disordered breathing (SDB) is common, but largely undiagnosed in the
general population. Information on demographic patterns of SDB occurrence and its …

Background Sleep-disordered breathing is a common condition associated with adverse
health outcomes including hypertension and cardiovascular disease. The overall objective …

Rationale: Sleep-disordered breathing recurrent intermittent hypoxia and sympathetic
nervous system activity surges provide the milieu for cardiac arrhythmia development …

Background: The health implications of regional differences in Medicare spending are
unknown. Objective: To determine whether regions with higher Medicare spending provide …

Background—Clinic-based observational studies in men have reported that obstructive
sleep apnea is associated with an increased incidence of coronary heart disease. The …