User profiles for "author:Danijela Gnjidic"
Danijela GnjidicUniversity of Sydney Verified email at sydney.edu.au Cited by 10124 |
A systematic review of the emerging definition of 'deprescribing'with network analysis: implications for future research and clinical practice.
Aims The aim of this study was to identify what definitions have been published for the term
'deprescribing', and determine whether a unifying definition could be reached. A secondary …
'deprescribing', and determine whether a unifying definition could be reached. A secondary …
Deprescribing trials: methods to reduce polypharmacy and the impact on prescribing and clinical outcomes
D Gnjidic, DG Le Couteur… - Clinics in geriatric …, 2012 - geriatric.theclinics.com
There are many challenges to ensuring good outcomes from the pharmacologic
management of older adults. With advancing age, the increased prevalence of diseases …
management of older adults. With advancing age, the increased prevalence of diseases …
Impact of deprescribing interventions in older hospitalised patients on prescribing and clinical outcomes: a systematic review of randomised trials
Background Polypharmacy and potentially inappropriate medications (PIMs) are prevalent
in older adults in hospital, and are associated with negative outcomes including adverse …
in older adults in hospital, and are associated with negative outcomes including adverse …
Reducing inappropriate polypharmacy: the process of deprescribing
Inappropriate polypharmacy, especially in older people, imposes a substantial burden of
adverse drug events, ill health, disability, hospitalization, and even death. The single most …
adverse drug events, ill health, disability, hospitalization, and even death. The single most …
Polypharmacy cutoff and outcomes: five or more medicines were used to identify community-dwelling older men at risk of different adverse outcomes
OBJECTIVE: This study aimed to determine an optimal discriminating number of
concomitant medications associated with geriatric syndromes, functional outcomes, and …
concomitant medications associated with geriatric syndromes, functional outcomes, and …
The effects of polypharmacy in older adults
An assessment of the safety and efficacy of multiple medications in older adults requires
clinically relevant objective outcomes and pharmacological measures of medication …
clinically relevant objective outcomes and pharmacological measures of medication …
High‐risk prescribing and incidence of frailty among older community‐dwelling men
Evidence about the association between treatment with high–risk medicines and frailty in
older individuals is limited. We investigated the relationship between high–risk prescribing …
older individuals is limited. We investigated the relationship between high–risk prescribing …
Prevalence and impact of fall-risk-increasing drugs, polypharmacy, and drug–drug interactions in robust versus frail hospitalised falls patients: a prospective cohort …
A Bennett, D Gnjidic, M Gillett, P Carroll, S Matthews… - Drugs & aging, 2014 - Springer
Background Several measures of medication exposure are associated with adverse
outcomes in older people. Exposure to and the clinical outcomes of these measures in …
outcomes in older people. Exposure to and the clinical outcomes of these measures in …
A systematic review of interventions to deprescribe benzodiazepines and other hypnotics among older people
Purpose Benzodiazepines are effective medicines for insomnia and anxiety but are
commonly used beyond recommended treatment time frames, which may lead to adverse …
commonly used beyond recommended treatment time frames, which may lead to adverse …
Drug Burden Index in older adults: theoretical and practical issues
Anticholinergic and sedative medications are commonly used in older adults and are
associated with adverse clinical outcomes. The Drug Burden Index was developed to …
associated with adverse clinical outcomes. The Drug Burden Index was developed to …