Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases
Klebsiella pneumoniae carbapenemases (KPCs) were originally identified in the USA in
1996. Since then, these versatile β-lactamases have spread internationally among Gram …
1996. Since then, these versatile β-lactamases have spread internationally among Gram …
Beta-lactamases in laboratory and clinical resistance
DM Livermore - Clinical microbiology reviews, 1995 - Am Soc Microbiol
beta-Lactamases are the commonest single cause of bacterial resistance to beta-lactam
antibiotics. Numerous chromosomal and plasmid-mediated types are known and may be …
antibiotics. Numerous chromosomal and plasmid-mediated types are known and may be …
CTX-M: changing the face of ESBLs in Europe
DM Livermore, R Canton, M Gniadkowski… - Journal of …, 2007 - academic.oup.com
Since around 2000—earlier in Poland and Spain and later in France and the UK—dramatic
shifts have occurred in the prevalence and types of extended-spectrum β-lactamases …
shifts have occurred in the prevalence and types of extended-spectrum β-lactamases …
[HTML][HTML] Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study
KK Kumarasamy, MA Toleman, TR Walsh… - The Lancet infectious …, 2010 - thelancet.com
Summary Background Gram-negative Enterobacteriaceae with resistance to carbapenem
conferred by New Delhi metallo-β-lactamase 1 (NDM-1) are potentially a major global health …
conferred by New Delhi metallo-β-lactamase 1 (NDM-1) are potentially a major global health …
Multiplex PCR for genes encoding prevalent OXA carbapenemases in Acinetobacter spp.
N Woodford, MJ Ellington, JM Coelho, JF Turton… - International journal of …, 2006 - Elsevier
Carbapenem resistance in Acinetobacter baumannii is a growing public health concern and
is most often mediated by OXA carbapenemases. We describe a novel multiplex polymerase …
is most often mediated by OXA carbapenemases. We describe a novel multiplex polymerase …
Dissemination of NDM-1 positive bacteria in the New Delhi environment and its implications for human health: an environmental point prevalence study
TR Walsh, J Weeks, DM Livermore… - The Lancet infectious …, 2011 - thelancet.com
Background Not all patients infected with NDM-1-positive bacteria have a history of hospital
admission in India, and extended-spectrum β-lactamases are known to be circulating in the …
admission in India, and extended-spectrum β-lactamases are known to be circulating in the …
Multiple Mechanisms of Antimicrobial Resistance in Pseudomonas aeruginosa: Our Worst Nightmare?
DM Livermore - Clinical infectious diseases, 2002 - academic.oup.com
Pseudomonas aeruginosa carries multiresistance plasmids less often than does Klebsiella
pneumoniae, develops mutational resistance to cephalosporins less readily than …
pneumoniae, develops mutational resistance to cephalosporins less readily than …
[HTML][HTML] Rapid evolution and spread of carbapenemases among Enterobacteriaceae in Europe
Plasmid-acquired carbapenemases in Enterobacteriaceae, which were first discovered in
Europe in the 1990s, are now increasingly being identified at an alarming rate. Although …
Europe in the 1990s, are now increasingly being identified at an alarming rate. Although …
The role of ISAba1 in expression of OXA carbapenemase genes in Acinetobacter baumannii
JF Turton, ME Ward, N Woodford… - FEMS microbiology …, 2006 - academic.oup.com
IS Aba1 was found in all widespread clones of Acinetobacter baumannii in the United
Kingdom. All isolates studied had a bla OXA-51-like carbapenemase gene; some also had …
Kingdom. All isolates studied had a bla OXA-51-like carbapenemase gene; some also had …
Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae …
H Grundmann, C Glasner, B Albiger… - The Lancet infectious …, 2017 - thelancet.com
Background Gaps in the diagnostic capacity and heterogeneity of national surveillance and
reporting standards in Europe make it difficult to contain carbapenemase-producing …
reporting standards in Europe make it difficult to contain carbapenemase-producing …