Background: Polypharmacy (ie, the use of multiple medications and/or the administration of
more medications than are clinically indicated, representing unnecessary drug use) is …

Prescription of medicines is a fundamental component of the care of elderly people, and
optimisation of drug prescribing for this group of patients has become an important public …

Investigators searched Medline and HealthSTAR databases from January 1, 1985 through
June 30, 1999 to identify articles on suboptimal prescribing in those age 65 years and older …

This study evaluated the reliability of a new medication appropriateness index. Using the
index, independent assessments were made of chronic medications taken by 10 …

Importance Many medications have anticholinergic effects. In general, anticholinergic-
induced cognitive impairment is considered reversible on discontinuation of anticholinergic …

Background Older people carry a high burden of illness for which medications are indicated,
along with increased risk of adverse drug reactions. We developed an index to determine …

PURPOSE: To evaluate the effect of sustained clinical pharmacist interventions involving
elderly outpatients with polypharmacy and their primary physicians. PATIENTS AND …

OBJECTIVE: To describe the prevalence, types, and consequences of adverse drug events
(ADEs) in older outpatients with polypharmacy. DESIGN: A cohort study. SETTING: General …

OBJECTIVES: To determine whether current use of central nervous system (CNS)‐active
medications, including benzodiazepines, antidepressants, anticonvulsants, and narcotics …

Abstract Objectives: The Air Primary Angioplasty in Myocardial Infarction (PAMI) study was
designed to determine the best reperfusion strategy for patients with high-risk acute …