Mechanochemistry: the mechanical activation of covalent bonds
MK Beyer, H Clausen-Schaumann - Chemical reviews, 2005 - ACS Publications
Regarding the activation of chemical reactions, today's chemist is used to thinking in terms of
thermochemistry, electrochemistry, and photochemistry, which is reflected in the …
thermochemistry, electrochemistry, and photochemistry, which is reflected in the …
Regulatory T cells in cancer
M Beyer, JL Schultze - Blood, 2006 - ashpublications.org
Increasing evidence supports the existence of elevated numbers of regulatory T cells (Treg
cells) in solid tumors and hematologic malignancies. Whereas the biology of CD4+ CD25+ …
cells) in solid tumors and hematologic malignancies. Whereas the biology of CD4+ CD25+ …
[HTML][HTML] A review of the potential climate change impacts and adaptation options for European viticulture
Viticulture and winemaking are important socioeconomic sectors in many European regions.
Climate plays a vital role in the terroir of a given wine region, as it strongly controls canopy …
Climate plays a vital role in the terroir of a given wine region, as it strongly controls canopy …
[PDF][PDF] Transcriptome-based network analysis reveals a spectrum model of human macrophage activation
Macrophage activation is associated with profound transcriptional reprogramming. Although
much progress has been made in the understanding of macrophage activation, polarization …
much progress has been made in the understanding of macrophage activation, polarization …
How strong is a covalent bond?
M Grandbois, M Beyer, M Rief, H Clausen-Schaumann… - Science, 1999 - science.org
The rupture force of single covalent bonds under an external load was measured with an
atomic force microscope (AFM). Single polysaccharide molecules were covalently anchored …
atomic force microscope (AFM). Single polysaccharide molecules were covalently anchored …
[PDF][PDF] Modulation of myelopoiesis progenitors is an integral component of trained immunity
Trained innate immunity fosters a sustained favorable response of myeloid cells to a
secondary challenge, despite their short lifespan in circulation. We thus hypothesized that …
secondary challenge, despite their short lifespan in circulation. We thus hypothesized that …
Innate immune memory in the brain shapes neurological disease hallmarks
Innate immune memory is a vital mechanism of myeloid cell plasticity that occurs in
response to environmental stimuli and alters subsequent immune responses. Two types of …
response to environmental stimuli and alters subsequent immune responses. Two types of …
Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine
M Beyer, M Kochanek, K Darabi, A Popov, M Jensen… - Blood, 2005 - ashpublications.org
Globally suppressed T-cell function has been described in many patients with cancer to be a
major hurdle for the development of clinically efficient cancer immunotherapy. Inhibition of …
major hurdle for the development of clinically efficient cancer immunotherapy. Inhibition of …
[PDF][PDF] Microbiome influences prenatal and adult microglia in a sex-specific manner
Microglia are embryonically seeded macrophages that contribute to brain development,
homeostasis, and pathologies. It is thus essential to decipher how microglial properties are …
homeostasis, and pathologies. It is thus essential to decipher how microglial properties are …
Specification of tissue-resident macrophages during organogenesis
INTRODUCTION Embryonic development and tissue homeostasis depend on cooperation
between specialized cell types. Resident macrophages are professional phagocytes that …
between specialized cell types. Resident macrophages are professional phagocytes that …