GRADE: an emerging consensus on rating quality of evidence and strength of recommendations

…, GE Vist, R Kunz, Y Falck-Ytter, P Alonso-Coello… - Bmj, 2008 - bmj.com
GRADE: an emerging consensus on rating quality of evidence and strength of
recommendations | The BMJ Skip to main content Intended for healthcare professionals Access …

Self-monitoring of oral anticoagulation: a systematic review and meta-analysis

C Heneghan, P Alonso-Coello, JM Garcia-Alamino… - The Lancet, 2006 - thelancet.com
Background Near-patient testing has made self-monitoring of anticoagulation with warfarin
feasible, and several trials have suggested that such monitoring might be equal to or better …

GRADE guidelines: 12. Preparing summary of findings tables—binary outcomes

…, J Meerpohl, B Djulbegovic, P Alonso-Coello… - Journal of clinical …, 2013 - Elsevier
Summary of Findings (SoF) tables present, for each of the seven (or fewer) most important
outcomes, the following: the number of studies and number of participants; the confidence in …

GRADE guidelines 6. Rating the quality of evidence—imprecision

…, AD Oxman, R Kunz, J Brozek, P Alonso-Coello… - Journal of clinical …, 2011 - Elsevier
GRADE suggests that examination of 95% confidence intervals (CIs) provides the optimal
primary approach to decisions regarding imprecision. For practice guidelines, rating down …

GRADE guidelines: 7. Rating the quality of evidence—inconsistency

…, J Brozek, M Helfand, P Alonso-Coello… - Journal of clinical …, 2011 - Elsevier
This article deals with inconsistency of relative (rather than absolute) treatment effects in
binary/dichotomous outcomes. A body of evidence is not rated up in quality if studies yield …

GRADE guidelines: 8. Rating the quality of evidence—indirectness

…, J Brozek, M Helfand, P Alonso-Coello… - Journal of clinical …, 2011 - Elsevier
Direct evidence comes from research that directly compares the interventions in which we
are interested when applied to the populations in which we are interested and measures …

GRADE guidelines: 9. Rating up the quality of evidence

…, S Sultan, P Glasziou, EA Akl, P Alonso-Coello… - Journal of clinical …, 2011 - Elsevier
The most common reason for rating up the quality of evidence is a large effect. GRADE
suggests considering rating up quality of evidence one level when methodologically …

GRADE guidelines: 4. Rating the quality of evidence—study limitations (risk of bias)

…, G Vist, R Kunz, J Brozek, P Alonso-Coello… - Journal of clinical …, 2011 - Elsevier
In the GRADE approach, randomized trials start as high-quality evidence and observational
studies as low-quality evidence, but both can be rated down if most of the relevant evidence …

[HTML][HTML] Aspirin in patients undergoing noncardiac surgery

…, DI Sessler, K Leslie, P Alonso-Coello… - … England Journal of …, 2014 - Mass Medical Soc
Background There is substantial variability in the perioperative administration of aspirin in
patients undergoing noncardiac surgery, both among patients who are already on an aspirin …

GRADE guidelines: 5. Rating the quality of evidence—publication bias

…, G Vist, R Kunz, J Brozek, P Alonso-Coello… - Journal of clinical …, 2011 - Elsevier
In the GRADE approach, randomized trials start as high-quality evidence and observational
studies as low-quality evidence, but both can be rated down if a body of evidence is …