User profiles for "author:R Kaul"

Rupert Kaul

Clinician scientist, University of Toronto
Verified email at utoronto.ca
Cited by 23012

[HTML][HTML] Citrus peel as a source of functional ingredient: A review

S Rafiq, R Kaul, SA Sofi, N Bashir, F Nazir… - Journal of the Saudi …, 2018 - Elsevier
Citrus plants belonging to the family Rutaceae which include fruits such as orange,
mandarin, lime, lemon, sour orange and grapefruitappear as a well known promising source …

[HTML][HTML] Intravaginal practices, bacterial vaginosis, and HIV infection in women: individual participant data meta-analysis

…, JM Baeten, J Brown, S Delany-Moretlwe, R Kaul… - PLoS …, 2011 - journals.plos.org
Background Identifying modifiable factors that increase women's vulnerability to HIV is a
critical step in developing effective female-initiated prevention interventions. The primary …

[HTML][HTML] A comparative review of HLA associations with hepatitis B and C viral infections across global populations

R Singh, R Kaul, A Kaul, K Khan - World journal of …, 2007 - ncbi.nlm.nih.gov
Hepatitis B (HBV) and hepatitis C (HCV) viral infection or co-infection leads to risk of
development of chronic infection, cirrhosis and hepatocellular carcinoma (HCC) …

[HTML][HTML] Integrative analysis of 111 reference human epigenomes

…, E Chuah, A Tam, TK Canfield, RS Hansen, R Kaul… - Nature, 2015 - nature.com
The reference human genome sequence set the stage for studies of genetic variation and its
association with human disease, but epigenomic studies lack a similar reference. To …

Systematic localization of common disease-associated variation in regulatory DNA

…, N Sotoodehnia, I Glass, SR Sunyaev, R Kaul… - Science, 2012 - science.org
Genome-wide association studies have identified many noncoding variants associated with
common diseases and traits. We show that these variants are concentrated in regulatory …

[HTML][HTML] The accessible chromatin landscape of the human genome

…, JD Lieb, SR Sunyaev, JM Akey, PJ Sabo, R Kaul… - Nature, 2012 - nature.com
DNase I hypersensitive sites (DHSs) are markers of regulatory DNA and have underpinned
the discovery of all classes of cis-regulatory elements including enhancers, promoters …

[HTML][HTML] Expanded encyclopaedias of DNA elements in the human and mouse genomes

…, J Adrian, T Kawli, CA Davis, A Dobin, R Kaul… - Nature, 2020 - nature.com
The human and mouse genomes contain instructions that specify RNAs and proteins and
govern the timing, magnitude, and cellular context of their production. To better delineate …

[HTML][HTML] A comparative encyclopedia of DNA elements in the mouse genome

…, DD Pervouchine, S Djebali, RE Thurman, R Kaul… - Nature, 2014 - nature.com
The laboratory mouse shares the majority of its protein-coding genes with humans, making it
the premier model organism in biomedical research, yet the two mammals differ in …

Mapping and sequencing of structural variation from eight human genomes

…, JC Mullikin, RK Wilson, L Bruhn, MV Olson, R Kaul… - Nature, 2008 - nature.com
Genetic variation among individual humans occurs on many different scales, ranging from
gross alterations in the human karyotype to single nucleotide changes. Here we explore …

Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients

…, SM Moskowitz, JL Burns, R Kaul… - Proceedings of the …, 2006 - National Acad Sciences
In many human infections, hosts and pathogens coexist for years or decades. Important
examples include HIV, herpes viruses, tuberculosis, leprosy, and malaria. With the exception …