Peroxisome proliferator-activated receptor α target genes
Peroxisome proliferator-activated receptors (PPARs) are nuclear proteins that belong to the
superfamily of nuclear hormone receptors. They mediate the effects of small lipophilic …
superfamily of nuclear hormone receptors. They mediate the effects of small lipophilic …
Roles of PPARs in health and disease
In developed societies, chronic diseases such as diabetes, obesity, atherosclerosis and
cancer are responsible for most deaths. These ailments have complex causes involving …
cancer are responsible for most deaths. These ailments have complex causes involving …
[HTML][HTML] Mechanisms of nutritional and hormonal regulation of lipogenesis
S Kersten - EMBO reports, 2001 - embopress.org
Fat build‐up is determined by the balance between lipogenesis and lipolysis/fatty acid
oxidation. In the past few years, our understanding of the nutritional, hormonal and …
oxidation. In the past few years, our understanding of the nutritional, hormonal and …
[PDF][PDF] Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans
Resveratrol is a natural compound that affects energy metabolism and mitochondrial
function and serves as a calorie restriction mimetic, at least in animal models of obesity …
function and serves as a calorie restriction mimetic, at least in animal models of obesity …
ATLAS pixel detector electronics and sensors
…, RD Kass, M Keil, S Kersten… - Journal of …, 2008 - iopscience.iop.org
The silicon pixel tracking system for the ATLAS experiment at the Large Hadron Collider is
described and the performance requirements are summarized. Detailed descriptions of the …
described and the performance requirements are summarized. Detailed descriptions of the …
[HTML][HTML] Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting
Prolonged deprivation of food induces dramatic changes in mammalian metabolism,
including the release of large amounts of fatty acids from the adipose tissue, followed by …
including the release of large amounts of fatty acids from the adipose tissue, followed by …
Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies—a consensus …
Recent advances in human genetics, together with a large body of epidemiologic,
preclinical, and clinical trial results, provide strong support for a causal association between …
preclinical, and clinical trial results, provide strong support for a causal association between …
Presence of genetic variants among young men with severe COVID-19
…, G van den Heuvel, T Mantere, S Kersten… - Jama, 2020 - jamanetwork.com
Importance Severe coronavirus disease 2019 (COVID-19) can occur in younger,
predominantly male, patients without preexisting medical conditions. Some individuals may …
predominantly male, patients without preexisting medical conditions. Some individuals may …
[HTML][HTML] Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene
Fasting is associated with significant changes in nutrient metabolism, many of which are
governed by transcription factors that regulate the expression of rate-limiting enzymes. One …
governed by transcription factors that regulate the expression of rate-limiting enzymes. One …
Biomass gasification in near-and super-critical water: status and prospects
Y Matsumura, T Minowa, B Potic, SRA Kersten… - Biomass and …, 2005 - Elsevier
The current status of biomass gasification in near-and supercritical water (SCWG) is
reviewed. There are two approaches to biomass gasification in supercritical water. The first …
reviewed. There are two approaches to biomass gasification in supercritical water. The first …