Recent advances targeting CCR5 for cancer and its role in immuno-oncology
X Jiao, O Nawab, T Patel, AV Kossenkov, N Halama… - Cancer research, 2019 - AACR
Experiments of nature have revealed the peculiar importance of the G-protein–coupled
receptor, CC chemokine receptor type 5 (CCR5), in human disease since ancient times. The …
receptor, CC chemokine receptor type 5 (CCR5), in human disease since ancient times. The …
Fosphenytoin: clinical pharmacokinetics and comparative advantages in the acute treatment of seizures
JH Fischer, TV Patel, PA Fischer - Clinical pharmacokinetics, 2003 - Springer
Fosphenytoin is a phosphate ester prodrug developed as an alternative to intravenous
phenytoin for acute treatment of seizures. Advantages include more convenient and rapid …
phenytoin for acute treatment of seizures. Advantages include more convenient and rapid …
Revisiting the recent applications of nanofiltration in food processing industries: Progress and prognosis
The use of nanofiltration (NF) in food processing industries has evolved from a novel
approach into a reliable and techno-economically attractive standard unit operation. The …
approach into a reliable and techno-economically attractive standard unit operation. The …
Dementia: What pharmacists need to know
S Duong, T Patel, F Chang - Canadian Pharmacists Journal …, 2017 - journals.sagepub.com
Dementia is a devastating disease that places a significant physical, emotional and financial
burden on patients, their caregivers and society. About 564,000 Canadians have dementia …
burden on patients, their caregivers and society. About 564,000 Canadians have dementia …
Hospital staff should use more than one method to detect adverse events and potential adverse events: incident reporting, pharmacist surveillance and local real-time …
S Olsen, G Neale, K Schwab, B Psaila… - BMJ Quality & …, 2007 - qualitysafety.bmj.com
Background: Over the past five years, in most hospitals in England and Wales, incident
reporting has become well established but it remains unclear how well reports match clinical …
reporting has become well established but it remains unclear how well reports match clinical …
[HTML][HTML] Inhibition of iNOS as a novel effective targeted therapy against triple-negative breast cancer
S Granados-Principal, Y Liu, ML Guevara… - Breast cancer …, 2015 - Springer
Introduction Triple-negative breast cancer (TNBC) is an aggressive form of breast cancer
with no effective targeted therapy. Inducible nitric oxide synthase (iNOS) is associated with …
with no effective targeted therapy. Inducible nitric oxide synthase (iNOS) is associated with …
A phase 1/2 clinical trial of the nitric oxide synthase inhibitor L-NMMA and taxane for treating chemoresistant triple-negative breast cancer
AW Chung, K Anand, AC Anselme, AA Chan… - Science translational …, 2021 - science.org
The inducible nitric oxide signaling (iNOS) pathway is associated with poor prognosis in
triple-negative breast cancer (TNBC). Prior studies using in vivo models showed that …
triple-negative breast cancer (TNBC). Prior studies using in vivo models showed that …
Screening for frailty in primary care: accuracy of gait speed and hand-grip strength
Objective To examine the accuracy of individual Fried frailty phenotype measures in
identifying the Fried frailty phenotype in primary care. Design Retrospective chart review …
identifying the Fried frailty phenotype in primary care. Design Retrospective chart review …
Efficacy of ixabepilone in ER/PR/HER2-negative (triple-negative) breast cancer
EA Perez, T Patel, A Moreno-Aspitia - Breast cancer research and …, 2010 - Springer
Abstract Patients with ER/PR/HER2-negative (triple negative) breast cancer are not
candidates for hormonal therapy or HER2-targeted agents. Ongoing research is aimed at …
candidates for hormonal therapy or HER2-targeted agents. Ongoing research is aimed at …
Demystifying serotonin syndrome (or serotonin toxicity)
AL Foong, KA Grindrod, T Patel, J Kellar - Canadian Family Physician, 2018 - cfp.ca
Objective To review the symptoms of serotonin toxicity (commonly referred to as serotonin
syndrome) and the causative drugs and their mechanisms of action, and to equip primary …
syndrome) and the causative drugs and their mechanisms of action, and to equip primary …