Background Several controlled studies provide evidence that treatment with interferon beta
in patients with a first event suggestive of multiple sclerosis (MS) delays conversion to …

Importance It remains unclear whether vitamin D insufficiency, which is common in
individuals with multiple sclerosis (MS), has an adverse effect on MS outcomes. Objectives To …

Background The aim of the Betaferon Efficacy Yielding Outcomes of a New Dose (BEYOND)
trial was to compare the efficacy, safety, and tolerability of 250 μg or 500 μg interferon beta-…

Background In most patients, severity of valvular aortic stenosis can be accurately assessed
non-invasively by echocardiography. However, retrograde catheterisation of the aortic valve …

Background The Betaferon/Betaseron in newly emerging multiple sclerosis for initial treatment
(BENEFIT) trial investigated the effect of treatment with interferon beta-1b after a clinically …

Recombinant immunoreceptors with specificity for the carcinoembryonic Ag (CEA) can
redirect grafted T cells to a MHC/Ag-independent antitumor response. To analyze receptor-…

Background Prediction of susceptibility to multiple sclerosis (MS) might have important
clinical applications, either as part of a diagnostic algorithm or as a means to identify high-risk …

Background Patients with a single episode of neurologic dysfunction and brain magnetic
resonance imaging (MRI) scans suggestive of multiple sclerosis are at high risk for clinically …

Carbohydrates such as sugar alcohols, monosaccharides, disaccharides, and other
oligosaccharides are separated as anions by ion exchange chromatography with a sodium …

Colorectal cancer represents the major cause for excess morbidity and mortality by malignant
disease in ulcerative colitis as well as in Crohn's disease. The risk for ulcerative colitis …