Importance Falls are the most common cause of injury-related morbidity and mortality among
older adults. Objective To systematically review literature on the effectiveness and harms of …

Background: Cardiovascular disease (CVD) is the leading cause of death in the United
States. Purpose: To update a systematic review about the benefits of aspirin for the primary …

Importance Low-dose aspirin is used for primary cardiovascular disease prevention and may
have benefits for colorectal cancer prevention. Objective To review the benefits and harms …

Background: The balance between potential aspirin-related risks and benefits is critical in
primary prevention. Purpose: To evaluate the risk for serious bleeding with regular aspirin use …

Background: Long-term follow-up of population-based randomized, controlled trials (RCTs)
has demonstrated that screening for abdominal aortic aneurysms (AAAs) measuring 3 cm or …

The major goal of the US Preventive Services Task Force (USPSTF) is to provide a reliable
and accurate source of evidence-based recommendations on a wide range of preventive …

Importance Hypertension is a major risk factor for cardiovascular disease and can be modified
through lifestyle and pharmacological interventions to reduce cardiovascular events and …

Importance Chronic obstructive pulmonary disease (COPD) is the third leading cause of
death in the United States. Objective To systematically review literature on the accuracy of …

Importance Ruptured abdominal aortic aneurysms (AAAs) have mortality estimated at 81%.
Objective To systematically review the evidence on benefits and harms of AAA screening …

The US Preventive Services Task Force (USPSTF), an independent panel that has provided
the gold standard for evidence-based guidelines in prevention for the past 2 decades, …